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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEBP2
All Species:
12.42
Human Site:
S125
Identified Species:
24.85
UniProt:
Q9Y5Z4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z4
NP_055135.1
205
22875
S125
D
P
P
R
P
L
E
S
D
V
F
I
E
D
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097682
116
12584
R42
P
G
S
Y
E
I
R
R
Y
G
P
A
K
W
V
Dog
Lupus familis
XP_541125
200
22361
S120
D
P
P
R
P
S
E
S
G
V
F
I
E
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU63
205
23044
S125
D
P
P
R
P
S
E
S
D
V
F
I
E
D
R
Rat
Rattus norvegicus
NP_001100985
203
22932
S123
D
P
P
R
P
S
E
S
D
V
F
I
E
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509287
187
20554
I112
P
V
E
S
N
V
F
I
E
D
R
P
G
M
T
Chicken
Gallus gallus
Q5ZMB2
189
21086
C114
Q
F
Q
A
S
P
P
C
P
S
D
E
S
I
K
Frog
Xenopus laevis
Q6NU05
190
21054
P112
P
S
Q
Y
Q
A
D
P
P
V
P
T
D
N
T
Zebra Danio
Brachydanio rerio
NP_956492
190
21471
P116
D
P
P
K
P
T
D
P
D
V
F
I
E
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300435
226
25339
L140
N
P
P
P
A
K
G
L
H
V
Q
R
W
Q
P
Maize
Zea mays
NP_001148314
219
23685
L131
D
P
P
P
A
E
G
L
R
V
D
R
W
A
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173153
232
25370
L147
D
P
A
P
S
E
N
L
H
I
Q
K
W
N
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
52.6
82.4
N.A.
83.9
81.4
N.A.
53.6
25.8
27.7
45.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
54.6
91.2
N.A.
90.7
90.2
N.A.
64.8
42.4
40.9
60.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
0
86.6
N.A.
93.3
93.3
N.A.
0
0
6.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
86.6
N.A.
93.3
93.3
N.A.
13.3
6.6
26.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
34.5
32.4
N.A.
35.3
N.A.
N.A.
Protein Similarity:
47.7
45.6
N.A.
46.5
N.A.
N.A.
P-Site Identity:
20
26.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
17
9
0
0
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
59
0
0
0
0
0
17
0
34
9
17
0
9
34
0
% D
% Glu:
0
0
9
0
9
17
34
0
9
0
0
9
42
0
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
0
42
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
17
0
9
9
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
9
0
9
0
42
0
9
0
% I
% Lys:
0
0
0
9
0
9
0
0
0
0
0
9
9
0
9
% K
% Leu:
0
0
0
0
0
9
0
25
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
9
0
9
0
0
0
0
0
0
17
0
% N
% Pro:
25
67
59
25
42
9
9
17
17
0
17
9
0
0
9
% P
% Gln:
9
0
17
0
9
0
0
0
0
0
17
0
0
9
0
% Q
% Arg:
0
0
0
34
0
0
9
9
9
0
9
17
0
0
42
% R
% Ser:
0
9
9
9
17
25
0
34
0
9
0
0
9
9
9
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
17
% T
% Val:
0
9
0
0
0
9
0
0
0
67
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
25
9
0
% W
% Tyr:
0
0
0
17
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _